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Optic perineuritis and orbital inflammation secondary to zoledronate: A case report


This is the first reported case of OPN linked to zoledronate. Prompt recognition and treatment of this rare adverse effe.... More

Consideration for a revised Gaussian-pencil-beam-model reported for calculation of the in-water d


The revised Gaussian pencil beam model is of practical use without using complicated correction factors .... More

Consideration for a revised Gaussian-pencil-beam-model reported for calculation of the in-water d


The revised Gaussian pencil beam model is of practical use without using complicated correction factors .... More

Massive localized lymphedema of the thigh: Pseudosarcoma of the morbidly obese


The final diagnosis was given based on patient’s demographics and the presence of lymphedema in other parts of the.... More

Further development of the preceding Gaussian-pencil-beam-model used for calculation of the in-wa


The further revised Gaussian pencil beam model is of practical use without using complicated correction factors .... More

Length of stay and 30 day mortality in patients suffering an uncomplicated ST-elevation...


24-hour mortality was very low in patients with an uncomplicated STEMI discharged after 2 nights in the hospital .... More

A revised Gaussian pencil beam model for calculation of the in-water dose caused by clinical elec


The revised Gaussian pencil beam model is of practical use and has a bright prospect to give almost the same calculation.... More

Voluntary organizations supporting patients with cancer: A qualitative exploratory study into the


The prime objective of cancer voluntary organizations is to decrease the impact of cancer on the personal life of patien.... More

Vulva and lower limb cancer: Results of inguinal lymph node staging on 81 cases


Chronic complications, including lymphedema are underestimated and require better assessment methods for prevention and .... More

Deuterium depletion inhibits lung cancer cell growth and migration in vitro and results


Results support earlier data that integration of D-depletion to conventional therapies increases the efficacy of therapy.... More

Fast magnetic resonance arthrography of the labrum


Fast MR arthrography using 3D VIBE sequences shows excellent concordance with standard T1-FS sequence for diagnosis of l.... More

Advances in artificial neural networks as a disease prediction tool


This review emphasizes the extensive potential of machine learning in medicine and the obstacles that must be overcome t.... More

Analytic continuation and incomplete data tomography


An alternative method to perform analytic continuation of an entire function, by using the Nyquist–Shannon samplin.... More

Survival benefit of revascularization versus optimal medical therapy....


CTO revascularization in diabetic patients, especially with CABG, was associated with lower long-term mortality rates as.... More

Scattered radiation during osteosynthesis of the distal radius: A phantom study


Phantom study shows that scattered radiation during osteosyntheses of the distal radius is negligible and therefore no p.... More

Fast filtered backprojection algorithm for low-dose computed tomography


A fast filtered backprojection (FBP) algorithm is introduced in this short paper. This algorithm is very simple and effe.... More

Unique challenges and the changing face of oncology during the COVID-19 pandemic and beyond


The unique challenges cancer specialists and those living with cancer face amidst the COVID-19 pandemic, as well as the .... More

Healthy farmer presenting with chest pain and bradycardia during peak COVID season


Managed to observe highest level protective measures, preventing him from acquiring COVID whilst surrounded by COVID pos.... More

Premature discontinuation of a randomized comparison between a new implant Dynaloc®

We found no differences in terms of limb length and other outcome measures between the groups at one year, which cannot .... More

Denoising COVID-19 computed tomography scans with scalable open source software


A method for denoising large 3D images that is functional, and based on methods currently in existing open source projec.... More

Variability in the metabolism of saccharides in bladder and colon cancer cell lines


The stimulation of growth by saccharides exhibits considerable variability with different molecules .... More

Iterative versus non-iterative image reconstruction methods for sparse magnetic resonance imaging


The images reconstructed by the iterative Bayesian algorithm may introduce more bias than the non-iterative algorithm, e.... More

Lack of clinically meaningful anatomical variations in bone marrow apparent diffusion coefficient


There was no clinically meaningful difference in apparent diffusion coefficient values across anatomical sites in diffus.... More

Novel biomarkers for tyrosine kinase inhibitor resistance in chronic myeloid leukemia patients: B


Expression levels of bioactive sphingolipid genes might be novel markers for determination of drug resistance in CML pat.... More

Lessons for the coronavirus (COVID-19) “not safe at any speed” thinking for the Unite


The FDA’s lack of adequate, timely attention to FQ safety concerns provides important lessons directly applicable .... More

MiR-381-3p inhibits proliferation, invasion and migration of hepatocellular carcinoma


miR-381-3p inhibits HCC cell proliferation, invasion and migration and may be a new therapeutic target for HCC. .... More

Whole-body magnetic resonance imaging for detection of malignant disease: A head-to-head-comparis


The diagnostic value of WB-MRI equaled whole-body 18F-FDG-PET/CT. The MRI approach could therefore be conside.... More

Low 5-hydroxymethylcytosine level is an independent predictor of high histological grade in local


Low 5hmC may serve as potential marker of adverse histopathological characteristics in locally advanced breast cancer pa.... More

A phase II, proof-of-concept pilot clinical study of a mouth rinse containing sandalwood album oi


The incidence of mucositis ≥3 from the historical data bases ranged from 22% to 70%. .... More

An analytical method for 3-dimensional calculation of the contaminant X-ray dose in water caused


it should be noted that the analytical method can give almost the same calculation results as the MC-based dose calculat.... More

Clinical pharmacology, use, and adverse reactions of intravenous iodinated contrast media in comp


This article describes the clinical pharmacology, use and adverse reactions of intravenous iodinated contrast media used.... More

Prognostic molecular biomarkers in endometrial cancer: A review


The use of biomarkers in the assessment of OS, RFS, and CSS requires large trials to expand our understanding of endomet.... More

Squamous cell carcinoma in situ of the endometrium - A case report with review of the lite


Both lesions were confirmed to have developed through a human papillomavirus (HPV) driven mechanism (p16, p40, HPV-16 po.... More

miR-21-5p protects IL-1β-induced human chondrocytes from degradation


MiR-21-5p might be a potential disease-modifying compound in OA, as it promotes hyaline cartilage production. These resu.... More

Self-medication among adult patients suffering from dental pain at the Yaoundé central hos


There is need to enforce formulate policies that can limit self-medication practices in the community. .... More

Variability in the induction of alkaline phosphatase by histone deacetylase inhibitors in bladder


The data suggested that regulation of alkaline phosphatase and dipeptidyl peptidase activities by histone deacetylase in.... More

Multilineage differentiating stress enduring (Muse)-like cells exist in synovial tissue


Muse-like cells can be isolated from the human synovial membrane, even from older patients, and therefore may provide a .... More

A newly discovered controversial role of the neutralizing HCV antibodies in the relapse of hepati


Important implications for the development of real therapeutic and prophylactic vaccine and also raise a great possibili.... More

HTLV-1 can be involved in acceleration of different nonhematological cancers


Findings support the hypotheses that HTLV-1 infection can be a common factor in the development of very different cancer.... More

Vestibular dysfunction as cortical damage with amyotrophic lateral sclerosis


A simple vestibular function test may be useful as a tool to objectively monitor the progression of cerebral lesions in .... More

Melanoma of unknown primary origin metastasizing to the ovary and breast: Case report and review


Making correct and timely diagnosis of metastatic melanoma followed by prompt targeted therapy significantly improved th.... More

Inflammatory myofibroblastic tumor of the uterus that might STUMP you: Report of a case with clin


IMT of the uterus might “STUMP” you. Be careful. The distinction between IMTs and other mesenchymal uterine .... More

Glycemic reduction alters white blood cell counts and inflammatory gene expression in diabetes


Significant glycemic reduction in subjects with poorly controlled diabetes led to reduced circulating WBC counts and inf.... More

The acceleration of metastases after tumor removal and the paradoxical phenomenon of concomitant


To elucidate the molecular basis of the phenomenon of CR might stimulate the design of new and less harmful means of man.... More

Computed tomography of congenital heart disease in patients with heterotaxy syndrome


Multidetector computed tomography allows to obtain detailed data on the morphology of the heart, great vessels, the anat.... More

Metastatic epithelioid hemangioendothelioma to the bone marrow with associated myelofibrosis rese


Epithelioid hemangioendothelioma presenting as a splenic mass with multiple foci of bone lesion and mimicking primary my.... More

Liver abscess after hepatic stereotactic body radiation therapy


Stereotactic body radiation therapy (SBRT) has emerged as an effective treatment approach because of the ability to focu.... More

Liver abscess after hepatic stereotactic body radiation therapy


Stereotactic body radiation therapy (SBRT) has emerged as an effective treatment approach because of the ability to focu.... More

Improving the stability of recombinant anthrax protective antigen vaccine


Finding suggests that modification of Asn713 and Asn719 of rPA to deamidation-resistant amino acid.... More

Ectopic liver tissue in the fundus of the stomach: A case report


Ectopic liver tissue is a rare occurrence in the thoracic and abdominal cavity. When identifying a well circumscribed su.... More

Ecological model links proto-oncogene to high incidence of metastatic cancers in African-American


The unusually high mortality rate of African-Americans from an aggressive sub-type of cancers that are generally fatal, .... More

Characterizing tobacco use in an American cancer center’s catchment area can help direct fu


This study shows how a cancer center can identify catchment area needs to plan research that reduces the burden of cance.... More

Colorectal cancer: Ageing, myeloid-derived suppressor cells, and treatment: Report of two cases

Immunological status is a useful, low invasive tool to identify the disease complexity and the results can be used in th.... More

Colorectal cancer: Ageing, myeloid-derived suppressor cells, and treatment: Report of two cases

Immunological status is a useful, low invasive tool to identify the disease complexity and the results can be used in th.... More

PCI for in-stent restenosis in a patient with acute coronary syndrome, cardiogenic shock and thro


Case report of percutaneous coronary intervention for in-stent restenosis in myelodysplastic syndrome .... More

3D-Image analysis of the impact of toothpaste abrasivity on the progression of simulated non-cari


3D-image subtraction was able to quantify and differentiate tooth loss, but only at advanced stages. The progression of .... More

Bosniak classification for complex renal cysts reevaluated: A systematic review


The effectiveness of the Bosniak classification system for complex renal cysts was high in categories II, IIF and IV, bu.... More

Bosniak classification for complex renal cysts reevaluated: A systematic review


The effectiveness of the Bosniak classification system for complex renal cysts was high in categories II, IIF and IV, bu.... More

Significance of small anteromedial or subpulmonic pneumothoraces on admission chest radiographs..


The presence of small anteromedial or subpulmonic PTX is associated with a difficult transition to extra-uterine life wh.... More

Bupropion overdose in adolescents: Three cases illuminating presentations and sequelae - A case s


Because of the multiple indications for bupropion use and an increase in its prescribing, it is important to recognize t.... More

Menopause and risk of kidney stones


Post-menopausal status is associated with higher risk of incident kidney stone. Natural and surgical menopause are each .... More

Clinical study of the treatment of multiple brain metastases from adenocarcinoma of the lung by s


Simultaneous integrated boost intensity-modulated radiotherapy (SIB) was superior to conformal radiotherapy (CRT), and p.... More

Cul-de-sac splenosis - An unusual location


This case highlights the value of a thorough clinical history in facilitating accurate diagnosis. .... More

Healing of femoral fractures by the meaning of an innovative intramedullary nail


Prosthesis suitable for elderly patients, having problems to effort the surgical intervention and to face risks related .... More

Healing of femoral fractures by an innovative intramedullary nail


Prosthesis suitable for elderly patients, having problems to effort the surgical intervention and to face risks related .... More

Primary osseous amyloidoma - Report of two cases with review of the literature


The misfolding and aggregation is secondary to significantly increased quantities of certain low molecular weight protei.... More

Novel approaches to percutaneous intervention in stage IV kidney disease


The lesion was treated using intravenous ultrasound to facilitate minimal-contrast percutaneous intervention and the pat.... More

The changing incidence of gonadal germ cell tumours


There is selective apoptosis in the developing ovary which could prevent the development of malignant germ cell tumours .... More

Combined treatment of gemcitabine with indole-3-carbinol or metformin on drug efficacy in pancrea


The sensitivity of GEM could depend on the method of treatment, whether cells were pre-treated with MET or I3C, which st.... More

Azathioprine induced Epstein-Barr virus positive mucocutaneous ulcer: A case report


The importance of recognizing this entity lies in its morphological and immunophenotypic overlap with classical Hodgkin&.... More

Usefulness of a balloon-expandable, covered stent for the transjugular intrahepatic portosystemic


The covered, balloon-expandable stent could be placed accurately and allowed creation of adapted shunts with smaller dia.... More

Prognostic serum biomarkers for colorectal cancer – Review


A general approach to understand how to predict clinical outcomes using risk, diagnostic, and prognostic biomarkers, is .... More

A comprehensive review of nephroblastoma with ureteric involvement


Even in advanced tumor stages, complete excision of the urinary tract tumor and optimal treatment of disseminated malign.... More

An anaplastic cardiac large cell lymphoma: A case report and analysis of cardiac involvement in n


The median progression-free survival and overall survival were nearly the same – approximately 3.5 years (range; 0.... More

Dosimetric comparison of radiation methods for palmar fibrosis


6-MeV electrons with individualized bolus gave superior CTV coverage over superficial radiotherapy at the 90% isodose li.... More

New salvage vincristine, carmustine, cyclophosphamide, and prednisone (VBCP) chemotherapy for rel


Results suggest VBCP is a highly active and tolerable salvage regimen among heavily pretreated MM patients who already f.... More

The first American cancer patient to receive dicycloplatin chemotherapy: A case report


These findings may explain DCP's more bearable side effects. Dicycloplatin may offer chemotherapeutic advantages ove.... More

Can vascular endothelial growth factor C expression be of use in predicting surgical stage or pro


Tumoral VEGF-C expression was not associated with higher surgical Stage or poorer prognosis in vulvar cancer. However, a.... More

Skin rash in patients treated with neoadjuvant erlotinib (Tarceva) in resectable non-small cell l


Recently developed test, for example “fluid phase biopsy” and “targeted next-generation” sequenc.... More

Some aspects of cancer biomarkers and their clinical application in solid tumors – revisite


Highlight the clinical applicability of some cancer biomarkers, as well as future approaches for their development and c.... More

Diagnostic problems and immune contexture in a case of cecal medullary carcinoma


An undifferentiated large bowel carcinoma characterized by black-tan color on gross examination, expressing epithelial k.... More

Long-term correction of diabetic hyperglycemia through glucose-responsive hepatic insulin product


Established the framework for a long-term, glucose-responsive treatment for T1DM from which further improvements can be .... More

The clinical and biological implications of the focal adhesion kinase pathway in ShenLingLan<


SLDM has a profound effect on the migratory and adhesive properties of ovarian cancer cells, potentially via inhibitory .... More

Feedback inhibition of apolipoprotein A-I synthesis by its propeptide in hepatocyte cell culture


Results suggest that the synthesis of apolipoprotein A-I is regulated by a feedback mechanism with its propeptide as inh.... More

Colitis and chronic bleeding in patients treated with dasatinib


Demonstrates a link between dasatinib and chronic colitis akin to inflammatory bowel disease, in patients undergoing the.... More

First application of ultrasound-assisted thrombolysis for acute....


By reducing the required dose of fibrinolytic, this report demonstrates the use of USAT as a potentially safe and effect.... More

Effect of anti-diabetic drug metformin on colorectal cancer cell lines


Metformin in pharmacological doses may not be an effective inducer of cell death in these colon cancer cell lines. Epifl.... More

Point of care ultrasound in cardiac arrest: A case report of PE in PEA arrest


Given this finding the patient was administered tPA, resulting in return of spontaneous circulation and eventual hospita.... More

10-MV X-ray dose calculation in water for MLC and wedge fields using a convolution method with X-


Convolution method can achieve accurate dose calculations even under MLC and/or wedge filtration. .... More

Burden, quality of life and distress of the main caregiver in head and neck, cervix and rectal ca


The little difference in the experience of caring within caregivers based on the three different cancer groups, although.... More

Effect of adhesive filler content on marginal adaptation of class II composite resin restorations


Filler contents of 30 wt% and 40 wt% significantly reduced the occurrence of severe gaps compared to 0 wt%. .... More

Combined treatment of refractory ascites by alfapumpTM and surgical umbilical hernia r


Implantation of the alfapump system resulted in control of ascites, improvement of nutritional status and quality of lif.... More

Reduction of radiation dose in adult CT-guided musculoskeletal procedures


Significant reduction in radiation dose without reduction in procedural accuracy can be achieved by simply lowering the .... More

The hydrocele of canal of Nuck: Case report and review of the literature


Painless inguinal swelling that may lead to investigation by imaging, mainly ultrasound, CT or MRI. .... More

KRAS testing and first-line treatment among patients diagnosed with metastatic colorectal


Despite NCCN guideline recommendations, 73% of mCRC cases diagnosed in 2011 had no documented KRAS test. Disparit.... More

Adopted Korean woman with symptoms of cystitis – Delayed diagnosis of tuberculosis leading


This case emphasizes the importance of continuing to include TB in the differential diagnosis of a variety of diseases, .... More

Comparison of the clinicopathologic features of solitary and multifocal papillary thyroid carcino


Most cases there are already histologic features that support a more aggressive behavior. .... More

Split-course chemoradiotherapy with S-1, a novel oral fluorouracil, and cisplatin for distant met


Split-course chemoradiotherapy with S-1 and cisplatin had an encouraging safety profile together with good efficacy .... More

Lumbosacral transcutaneous electrical stimulation in children with slow transit constipation: A p


This new method of TESIC for STC warrants further evaluation in a randomised, controlled trial. .... More

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